Child’s Weight (pounds) 20-24 25-37  38-49  50-99  100+   lbs 
 Liquid 12.5 mg/1 teaspoon (tsp) 3/4 1 1 1/2 2 tsp
 Liquid 12.5 mg/5 milliliters (ml) 4 5 7.5 10 ml
 Chewable 12.5 mg 1 1 1/2 2 4 tablets
 Tablets 25 mg 1/2 1/2 1 2 tablets
 Capsules 25 mg 1 2 caps

Indications: Treatment of allergic reactions, nasal allergies, hives and itching.

Table Notes:
AGE LIMITS: For allergies, don’t use under 1 year of age (Reason: it’s a sedative). For colds, not recommended at any age (Reason: no proven benefits) and should be avoided if under 4 years old. Avoid multi-ingredient products in children under 6 years of age (Reason: FDA recommendations 10/2008).
DOSAGE: Determine by finding child’s weight in the top row of the dosage table
MEASURING the DOSAGE: Syringes and droppers are more accurate than teaspoons. If possible, use the syringe or dropper that comes with the medication. If you use a teaspoon, it should be a measuring spoon. Regular spoons are not reliable. Also, remember that 1 level teaspoon equals 5 ml and that ½ teaspoon equals 2.5 ml.
FREQUENCY: Repeat every 6 hours as needed
ADULT DOSAGE: 50 mg
CHILDREN’S BENADRYL FASTMELTS: Each fastmelt tablet contains the equivalent of 12.5 mg of Diphenhydramine HCL and dosed the same as chewable tablets

Last Updated
5/5/2015
Source: www.healthychildren.org
My Child Is Sick! Expert Advice for Managing Common Illnesses and Injuries (Copyright © 2011 Barton D. Schmitt, MD, FAAP)